Stem Cells

This weeks #Fridayread describes a feeder cell-free culture system based on serum coating that supports long-term maintenance of naive human pluripotent stem cells (hPSCs).

Commercial media preparations can be a convenient option for stem cell and organoid maintenance and differentiation, but the proprietary 'black box' formulation prohibits trouble-shooting and optimization read our blog, as we ask, what's in it?

In this recently revised and expanded paper from our collaborators in the Bertero lab, Truszkowski et al. have described a cost-effective homemade media recipe for the culture of human pluripotent stem cells (hPSCs), this adds to the evidence that homemade media using Qkine growth factors can be a suitable replacement for, or improvement on, commercially available media.

For the cultivated meat industry, the goal is to produce a quality raw material quickly and at a reduced cost. At WildBio, with help from Qkine, we are harnessing the power of cells from wild game species in South Africa.

This recent publication in collaboration with Qkine focusses on the optimization of home-brew media for the maintenance of human induced pluripotent stem cells (hiPSCs), using Qkine growth factors to allow cost-effective, practical, and reproducible culture of hiPSCs. Qkine thermostable tag-free FGF2-G3 proteins were found to be highly bioactive, necessitating an 8-fold reduction in concentration for the short (145 aa) form of FGF2-G3 in the optimized media.

Hematopoietic stem cells (HSCs) are at the forefront of a transformative shift in modern medicine, beginning to revolutionize patient care by offering novel therapeutic treatments for a wide range of diseases. This review blog summarizes advances in the clinical use of HSCs in HSC transplantation.

Qkine is a company run by scientists, and the science is the focus of everything we do. Our theme at ISSCR this year was stress-free stem cell culture - exploring how suppliers of recombinant proteins can proactively improve the quality, availability and functionality of growth factors to generate experimental outcomes faster, easier and more efficiently.

Reflections on the dynamic ISSCR 2024 workshop on Standards for Human Stem Cell Use in Research including recommendations for growth factor supply chains for raw (ancillary materials) for cell therapy and ATMP manufacture.

Specialist bioactive growth factor protein manufacturer Qkine today announced a new partnership with StemCultures, a life sciences company dedicated to developing innovative reagents that enhance the quality and efficiency of cell growth and differentiation in culture.

Qkine collaborates with the Cambridge Stem Cell Institute to facilitate same-day access to key research products for researchers at the Cambridge Biomedical Campus

This month: Bovine/porcine FGF-2 out now, Qkine scale up manufacturing, why you should check vial recovery as part of your QC, and our latest blog article on our internship.

This month: download our latest poster on human pluripotent stem cell-directed differentiation, read a recent review article on human organoids and visit us in person at one of our upcoming events