R-spondin family (RSPO)

R-spondin family (RSPO) includes 4 secreted glycoproteins (R-spondin 1, R-spondin 2, R-spondin 3, R-spondin 4). Implicated in the activation and regulation of the Wnt signaling pathway, RSPO proteins contribute significantly to various biological processes throughout embryonic development, adult tissue maintenance, and the onset of disease. This family of secreted proteins is also used widely in organoid culture.

Qkine robust animal-free manufacturing platform, along with rigorous quality control procedures, ensure that all our r-spondin proteins are:

  • animal origin-free (AOF) and carrier protein-free
  • highly pure (>98%, by SDS-PAGE quantitative densitometry)
  • highly bioactive (equally or more bioactive than other dominant suppliers) and come with our Bioactivity Guarantee
  • highly reproducible with excellent lot-to-lot consistency

Qkine is committed to manufacturing bioactive proteins of the highest quality to enhance scientific outcomes and improve reproducibility. Our stringent quality control procedures in place ensure your results are reliable and reproducible every time.  We couple this with unrivaled lot-to-lot consistency, ensuring every single batch meets the same quality standards as all previous ones, thereby reducing the need for batch testing. All our products rigorously adhere to the Nine-point Qkine Quality Commitment.

Please contact us if you have any questions. Our dedicated team of stem cell specialists is available to answer any queries.

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R-spondins

    Vial image R-spondin 1

    Recombinant human R-spondin 1 protein (Qk006)

    Potentiates Wnt signaling in many organoid culture systems including intestinal and tumor (cancer) organoid culture.

    Price range: £190.00 through £2,090.00
    View product This product has multiple variants. The options may be chosen on the product page

    Qk031 R-spondin LR5 vial image

    Recombinant human R-spondin 1 LR5 protein (Qk031)

    Engineered protein which activates Wnt signaling only in the LGR5+ stem cell population.

    Price range: £190.00 through £2,090.00
    View product This product has multiple variants. The options may be chosen on the product page

    Qk032 R-spondin 3 vial image

    Recombinant human R-spondin 3 protein (Qk032)

    Potentiates Wnt signaling and can be used alongside R-spondin 1 in intestinal organoid culture systems.

    Price range: £190.00 through £2,090.00
    View product This product has multiple variants. The options may be chosen on the product page

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